Set during the 1960s in an alternate New Zealand known as Nuovo Zelandia, "Perfect Creature" imagines a world where vampires and humans peacefully co-exist, with the bloodsuckers the next step in human evolution. This delicate balance looks to be destroyed when an influenza epidemic begins to sweep the human population and one vampire turns to preying on humans. The church sends out Silus (Scott) to catch the renegade vampire, Edgar. Silus joins forces with a human police captain (Burrows), and discovers that Edgar harbors dark secrets.