Robert De Niro portrays a widowed father who desperately tries to break through to his 9-year-old daughter when she creates a creepy, maniacal imaginary friend with a terrifying vendetta.

Two-time Academy Award(R)-winning De Niro is Dr. David Callaway, Ph.D., a psychologist and father trying to help his daughter Emily, played by Dakota Fanning, deal with the trauma of her mother's death. Famke Janssen is Katherine, a child psychiatrist and colleague of David. Elisabeth Shue is Elizabeth, a divorced woman who befriends David and Emily. Melissa Leo and Robert John Burke are Laura and Steven, their next door neighbors who are struggling with the death of their own young daughter.