When an accidental concussion awakens the carnal urges of Sylvia Stickles (Tracey Ullman), the people of Pinewood become pitted against each other in an epic battle of decency (Neuters) versus depravity (Sex Addicts). With her talented go-go dancing daughter (Selma Blair) and devoted husband, Vaughn (Chris Isaak), by her side, along with tow-truck driver and sexual healer Ray-Ray Perkins (Johnny Knoxville) as her guide, Sylvia finds herself on the road to eternal sexual satisfaction. The Neuters never had a chance!