Crank (2006)

As it turns out, Chev is a hit man who freelances for a major West Coast syndicate. A run of the mill job the night before instead went awry: he let his target slip away in an effort to quit professional killing and start a new life with his girlfriend Eve.

Now, Chev must keep moving to stay alive: the only way to prolong the poison from stopping his heart is to keep his adrenaline flowing. As the clock ticks, Chelios cuts a swath through the streets of Los Angeles, wreaking havoc on those who dare stand in his way. He must rescue Eve from danger, stay two steps ahead of his nemeses and search for an antidote to save his own life.