Matthew started his career in 1996 as a producer with The Innocent Sleep, a thriller starring Michael Gambon and Rupert Graves.

He set up Ska Films with director Guy Ritchie in 1997 and the following year made Lock Stock and Two Smoking Barrels, which took in excess of 11m in the UK alone, becoming one of the most successful British films of the decade.

This was followed by the diamond heist movie, Snatch, (2000) with Brad Pitt, Benicio Del Toro and Jason Statham. Snatch opened to great acclaim, taking 3 million in the UK in its opening weekend (the largest ever opening for an 18 certificate film) and 12 million total UK box office. The film went on to accrue $100 million worldwide.

In 2002 Vaughn produced Mean Machine, a remake of the 1974 Burt Reynolds classic The Longest Yard, starring Vinnie Jones and Jason Statham followed by Swept Away starring Madonna and Adrianno Giannini and directed by Guy Ritchie.

Layer Cake marks his directorial debut.