Bradford was most recently seen in Merchant/Ivory's Heights, opposite Glenn Close, James Marsden, and Elizabeth Banks. Prior to that, he starred in Don Roos's Happy Endings opposite Lisa Kudrow.

Bradford will soon start production on Yann Samuell's My Sassy Girl, a remake of the hit South Korean romantic comedy. Bradford will star opposite Elisha Cuthbert.

Bradford is well known for his roles in Peyton Reed's Bring it On, opposite Kirsten Dunst, and John Polson's thriller Swimfan, opposite Erika Christensen. Both films debuted at No. 1 at the box office, in August 2000 and September 2002 respectively.

Bradford made his breakthrough performance in Steven Soderbergh's acclaimed King of the Hill. His role in this film garnered him a Best Actor nomination by the Chicago Film Critics. Bradford's other film credits include: James Ivory's A Soldier's Daughter Never Cries, Iain Softley's Hackers, Baz Luhrmann's Romeo and Juliet, Michael Radford's Dancing at the Blue Iguana, and Nickolas Perry's Speedway Junky.

On television, Bradford guest starred on NBC's Emmy winning drama, The West Wing as Ryan Pierce, the intern to Joshua Lyman (Bradley Whitford).

Bradford graduated from Columbia University in New York and currently resides in Los Angeles.