Bob Hoskins was nominated for an Academy Award, and won the Golden Globe, BAFTA, New York Film Critics Circle, Los Angeles Film Critics Association, National Society of Film Critics, Boston Society of Film Critics, and Cannes International Film Festival's Best Actor Awards, for his performance in Neil Jordan's Mona Lisa.

His numerous film credits also include John Mackenzie's The Long Good Friday (for which he received a BAFTA Award nomination) and Beyond the Limit (a.k.a. The Honorary Consul, for which he received a BAFTA Award nomination); Alan Parker's Pink Floyd – The Wall; Francis Ford Coppola's The Cotton Club (his previous film with his Hollywoodland leading lady Diane Lane); Terry Gilliam's Brazil; Robert Zemeckis' blockbuster Who Framed Roger Rabbit (for which he received a Golden Globe Award nomination); Richard Benjamin's Mermaids; Steven Spielberg's Hook; Oliver Stone's Nixon; Nora Ephron's Michael; Christopher Hampton's The Secret Agent (which he also executive-produced); Shane Meadows' TwentyFourSeven (for which he won a European Film Award) and A Room for Romeo Brass; Atom Egoyan's Felicia's Journey; Jean-Jacques Annaud's Enemy at the Gates; Fred Schepisi's Last Orders; Wayne Wang's Maid in Manhattan; Mira Nair's Vanity Fair (also a Focus Features release); Kevin Spacey's Beyond the Sea; Louis Leterrier's Unleashed (a Rogue Pictures release); and Stephen Frears' Mrs. Henderson Presents (which he also executive-produced, and for which he received Golden Globe and British Independent Film Award nominations). He recently wrapped production on Nick Love's Outlaw, in which he stars with Sean Bean.

Mr. Hoskins directed the features The Raggedy Rawney (which he also wrote and starred in) and Rainbow (which he also starred in), as well as episodes of the television series Tube Tales and Tales from the Crypt (also starring in the latter).

His notable television credits also include Dennis Potter's classic miniseries Pennies from Heaven (directed by Piers Haggard, and for which he received a BAFTA Award nomination), as well as Peter Yates' telefilm Don Quixote and Roger Spottiswoode's telefilm Noriega: God's Favorite.

At the 2004 British Independent Film Awards, Mr. Hoskins was honored with the Richard Harris Award for Outstanding Contribution by an Actor to British Film.